Course Title: CE Workshop 02 - Update on Vascular Contributions to Cognitive Impairment and Dementia (Nation)


Credit Hours: 3


Instructor(s) Daniel Nation


Daniel Nation, PhD
Associate Professor of Psychological Science
University of California Irvine

CE Workshop # 2:


Update on Vascular Contributions to Cognitive Impairment and Dementia

Abstract & Learning Objectives:

Vascular contributions to cognitive impairment and dementia are increasingly recognized in terms of the importance and scope of the problem facing older adults at risk for dementia. Rapid and recent developments in the field include new discoveries in the epidemiology, neuropathology, neuroimaging and neuropsychological aspects of vascular disease. These recent insights have triggered major shifts in the nosology of these disorders and their differential diagnosis with major implications for case conceptualization in clinical practice. This update will include recent developments in the clinical science of vascular cognitive disorders with implications for clinicians and scientists focused on assessment, diagnosis and therapeutic approaches to cognitive impairment and dementia in older adults.


Upon conclusion of this course, learners will be able to:

  • Analyze epidemiology of vascular contributions to cognitive impairment and dementia
  • Discuss neuropathology and neuroimaging of cerebrovascular disease
  • Apply diagnostic principles and analyze neuropsychological profiles of vascular disease
  • Assess status of therapeutic approaches and predict future research directions

Speaker Biography:

Dr. Daniel Nation is an Associate Professor of Psychological Science at the University of California Irvine (UCI), where he holds an appointment at the UCI Institute for Memory Impairments and Neurological Disorders (UCI MIND). Dr. Nation's research focuses on vascular contributions to cognitive impairment and dementia, with particular emphasis on preclinical biomarkers of cerebrovascular dysfunction and microvascular pathology. He is currently leading multiple studies funded by the National Institutes of Health (NIH) to improve our understanding of the independent contribution of vascular factors to cognitive dysfunction in older adults. Studies include those focused on the role of increased blood-brain barrier permeability and increased cerebrovascular resistance, as well as the potentially protective role of circulating vascular stem cells.