Christine Mrakotsky, Ph.D.
CE 2: Stroke in Neonates and Children: Ischemic Injury and Its Impact on Neurodevelopment
Stroke- long recognized as an adult condition- is an important cause of acquired brain injury in children, occurring most commonly in the neonate and throughout childhood. Ischemic injury due to restriction of blood flow accounts for the majority of infarcts in newborns, and half of childhood strokes. Cause and presentation differs from adult stroke, leading to delay in diagnosis and treatment, and consequently to significant physical, cognitive, and emotional long-term morbidities. Among main risk factors, new evidence points to the involvement of infection and inflammatory processes in the pathophysiology of ischemic stroke, potentially impacting neuropsychological outcomes. This course will review cause, risk factors and presentation of perinatal vs. childhood arterial ischemic stroke, cognitive and behavioral consequences at different ages, and risk factors contributing to cognitive, emotional, and adaptive development. Clinical implications of stroke outcomes for school, psychosocial and family functioning will be described. In a final part, neuropsychological assessment models in acute and long-term care, as well as current interventions to facilitate recovery and development will be discussed along with the need for targeted research.
This workshop is designed to help you
  1. List the main causes and risk factors of pediatric stroke, including contributions of inflammation and infection to stroke etiology
  2. Describe cognitive and emotional outcomes of pediatric stroke at different ages, and risk factors
  3. Discuss acute and long-term neuropsychological assessment models and current standards of intervention