Course Title: CE 07: On the Bright Side of Memory Aging: Brain Maintenance (Nyberg)


Credit Hours: 1.5


Instructor(s) Lars Nyberg


Lars Nyberg, PhD Professor of Neuroscience Medical Faculty, Umeå University
CE Workshop # 7: On the Bright Side of Memory Aging: Brain Maintenance
Abstract & Learning Objectives: The aging brain undergoes many changes that can impact memory and cognition, but longitudinal studies show that some older adults display brain maintenance, or relative lack of senescent brain changes and age-related brain pathology. This workshop is focused on structural and functional maintenance of the hippocampus complex, as hippocampal maintenance is a key determinant of well-preserved episodic-memory functioning in older age. Several potential neural and non-neural mechanisms promoting hippocampal maintenance will be considered, including neuronal survival and neurogenesis, intact neuronal morphology, and vascular integrity. Evidence will be reviewed that suggest that correlated genetic and environmental factors influence the operation of these maintenance mechanisms, partly through lifestyle choices. Upon conclusion of this course, learners will be able to:
  • Describe the heterogeneity in episodic-memory change in aging and in age-related changes of critical structures in the medial temporal lobe that support episodic memory
  • Discuss leading edge longitudinal research techniques for investigating trajectories of change
Speaker Biography: Lars Nyberg serves as Professor of Psychology and Neurosciences at Umeå University, Sweden. He has been active in the field of functional neuroimaging of memory since 1994. He is the director of Umeå Center for Functional Brain Imaging (UFBI), and a principal investigator of the Betula longitudinal project on aging, memory and dementia. Since 2008 he is a member of the Royal Swedish Academy of Sciences. Nyberg’s research is focused on the identification of genetic, brain, and life-style predictors of heterogeneity in cognitive-aging profiles.