Visit NavNeuro at:

Episode 49 | Pediatric Cardiac Arrest with Dr. Beth Slomine


There is a growing need for neuropsychologists in an inpatient rehab setting and throughout follow-up care for children who are resuscitated after experiencing a cardiac arrest. Today, we talk with Beth Slomine, Ph.D., ABPP-CN, about the risks and benefits associated with therapeutic hypothermia for these children, and her involvement in the THAPCA multi-site trial.

apa-logo_white_screenThe International Neuropsychological Society is approved by the American Psychological Association to sponsor continuing education for psychologists. The International Neuropsychological Society maintains responsibility for this program and its content.

Beth Slomine
Instructor Credentials

Dr. Beth Slomine is co-director of the Center for Brain Injury Recovery and director of neuropsychology training and neuropsychological rehabilitation services at Kennedy Krieger Institute. She is an associate professor of Psychiatry & Behavioral Sciences and Physical Medicine & Rehabilitation at Johns Hopkins University School of Medicine. She is a licensed psychologist, board certified clinical neuropsychologist, and board-certified subspecialist in pediatric neuropsychology. Research interests include developing neurobehavioral assessment tools and understanding factors influencing outcome following pediatric neurological injury. Dr. Slomine has authored more than 70 peer-reviewed manuscripts, numerous book chapters, and co-edited a textbook entitled Cognitive Rehabilitation for Pediatric Neurological Conditions.

Topics Covered
  • Defining terminology - cardiac arrest, hypothermia, normothermia, and therapeutic hypothermia after pediatric cardiac arrest (THAPCA)
  • Beth discusses how cardiac arrest impacts brain functioning
  • She also explains the risks and benefits associated with THAPCA
  • Delayed access to medical care is the strongest predictor of poor outcomes in pediatric cardiac arrest
  • Beth suggests that children with in-hospital and out-of-hospital cardiac arrest are distinct populations due to outcome differences
  • Sampling bias is a significant limitation in THAPCA clinical trials
  • Beth discusses important ethical considerations of withholding therapeutic hypothermia
  • Preexisting factors associated with survival rate and neurobehavioral outcomes in THAPCA
  • Cognitive functioning in pediatric cardiac arrest
  • Beth explains the role of a neuropsychologist in an interdisciplinary medical team
  • Bonus questions
Educational Objectives
  • Define and distinguish cardiac arrest and heart attack.
  • Discuss the utility of targeted temperature management for pediatric cardiac arrest.
  • Describe the design and results of the therapeutic hypothermia after pediatric cardiac arrest (THAPCA) trial.
  • Identify the predictors of poor outcomes in pediatric cardiac arrest.
  • List two preexisting factors associated with survival and neurobehavioral outcomes in THAPCA.
  • Apply knowledge about pediatric cardiac arrest and therapeutic hypothermia in clinical evaluations with children.
Target Audience
  • Introductory
  • Date Available: 2021-05-03
  • You may obtain CE for this podcast at any time.
Offered for CE
  • Yes
  • Members $20
  • Non-Members $25
Refund Policy
  • This podcast is not eligible for refunds
CE Credits
  • 1.0 Credit(s)
  • N/A
  • N/A
  • Holubkov, R., Clark, A. E., Moler, F. W., Slomine, B. S., Christensen, J. R., Silverstein, F. S., et al. (2015). Efficacy outcome selection in the therapeutic hypothermia after pediatric cardiac arrest trials. Pediatr Crit Care Med, 16(1), 1-10.
  • Moler, F. W., Silverstein, F. S., Meert, K. L., Clark, A. E., Holubkov, R., Browning, B., et al. (2013). Rationale, timeline, study design, and protocol overview of the therapeutic hypothermia after pediatric cardiac arrest trials. Pediatr Crit Care Med, 14(7), e304-315.
  • Pemberton, V. L., Browning, B., Webster, A., Dean, J. M., & Moler, F. W. (2013). Therapeutic hypothermia after pediatric cardiac arrest trials: the vanguard phase experience and implications for other trials. Pediatr Crit Care Med, 14(1), 19-26.
  • Schmitt, K. R., Tong, G., & Berger, F. (2014). Mechanisms of hypothermia-induced cell protection in the brain. Mol Cell Pediatr, 1(1), 7.
  • Slomine, B. S., Silverstein, F. S., Christensen, J. R., Holubkov, R., Page, K., Dean, J. M., et al. (2016). Neurobehavioral Outcomes in Children After Out-of-Hospital Cardiac Arrest. Pediatrics, 137(4).