Dr. Yaakov Stern, Ph.D., is the Florence Irving Professor of Neuropsychology in the Departments of Neurology, Psychiatry, and Psychology, and the Taub Institute for the Research on Alzheimer’s Disease and the Aging Brain. Dr. Stern is chief of the Cognitive Neuroscience Division in the Department of Neurology.
Dr. Stern’s research focuses on cognition in normal aging and in diseases of aging, particularly Alzheimer’s disease. A strong theme in his research is exploring individual differences in task performance in general and, more specifically, the reason why some individuals show more cognitive deficit than others in the face of brain insult. This has led to the cognitive reserve hypothesis, which provides rationale for intervening to improve cognitive aging. He directs the Reference Ability Neural Network study, a large-scale longitudinal study designed to isolate brain activation and morphological features associated with specific cognitive abilities. He has directed several clinical trials and is currently also involved in several additional, ongoing studies of cognition in normal aging, studies of the heterogeneity of Alzheimer’s disease and epidemiologic studies of aging, Alzheimer’s disease incidence and progression His research approach includes classic neuropsychological and cognitive experimental techniques with a strong focus on functional imaging. He has published over 600 peer-reviewed papers, numerous chapters, and edited a book on cognitive reserve.